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Article

Aup1-mediated Regulation of Rtg3 during Mitophagy

20 Oct 2009

Abstract excerpt

Mitophagy is an autophagic process that degrades mitochondria by an intracellular engulfment that leads to their delivery into the lumen of the cell's hydrolytic compartment, such as the lysosome in animal cells or the vacuole in yeast. It is hypothesized that such processes serve a quality control function to prevent or slow the accumulation of malfunctioning mitochondria, which are thought in turn to underlie...

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Share to Autophagy in Disease and Therapy
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PMID: 19840933
DOI: 10.1074/jbc.m109.048140

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