Article
Apg2p functions in autophagosome formation on the perivacuolar structure.
The Journal of biological chemistry - 10 Aug 2001
Shintani T, Suzuki K, Kamada Y, Noda T, Ohsumi Y
Abstract excerpt
Autophagy is a degradative process in which cytoplasmic components are non-selectively sequestered by double-membrane structures, termed autophagosomes, and transported to the vacuole. We have identified and characterized a novel protein Apg2p essential for autophagy in yeast. Biochemical and fluorescence microscopic analyses indicate that Apg2p functions at the step of autophagosome formation. Apg2p localizes to...
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