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Article

Dissection of autophagosome biogenesis into distinct nucleation and expansion steps.

The Journal of cell biology - 27 Nov 2000

Abeliovich H, Dunn W A, Kim J, Klionsky D J

Abstract excerpt

Rapamycin, an antifungal macrolide antibiotic, mimics starvation conditions in Saccharomyces cerevisiae through activation of a general G(0) program that includes widespread effects on translation and transcription. Macroautophagy, a catabolic membrane trafficking phenomenon, is a prominent part of this response. Two views of the induction of autophagy may be considered. In one, up-regulation of proteins involved...

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Identifiers

PMID: 11086004
DOI: 10.1083/jcb.151.5.1025
PMCID: PMC2174351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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