Sexual dysfunction and sudden death in epileptic male EL mice: inheritance and prevention with the ketogenic diet.

doi:10.1046/j.1528-1157.2003.11402.x

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Article

Sexual dysfunction and sudden death in epileptic male EL mice: inheritance and prevention with the ketogenic diet.

Epilepsia - 1 Jan 2003

Todorova Mariana T, Dangler Charles A, Drage Michael G, Sheppard Barbara J, Fox James G, Seyfried Thomas N

Abstract excerpt

PURPOSE: The EL mouse is an animal model for multifactorial idiopathic epilepsy. Although EL mice have been studied extensively for >45 years, the etiology of male sudden death and its relation to seizures have not been defined. Here we investigated the cause of EL male sudden death and its relation to epilepsy. METHODS: For histopathologic analysis, the terminally ill EL mice (n = 15) were killed, and the...

Topics

Animals
Blood Urea Nitrogen
Chromosome Aberrations
Crosses, Genetic
Death, Sudden
Dietary Fats
Disease Susceptibility
Ejaculation
Electrolytes
Epilepsy, Complex Partial
Epilepsy, Generalized

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genes, Recessive

Genetic Markers

Genetic Predisposition to Disease

Kidney

Male

Mice

Source

Open in PubMed

Identifiers

PMID: 12581226
DOI: 10.1046/j.1528-1157.2003.11402.x

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