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Article

Establishment of a Transgenic Sickle-Cell Mouse Model to Study the Pathophysiology of Priapism

11 Jun 2009

Abstract excerpt

INTRODUCTION: Priapism is a poorly understood disease process with little information on the etiology and pathophysiology of this erectile disorder. One group of patients with a high prevalence of priapism is men with sickle-cell disease. AIM: Establish an in vivo transgenic sickle-cell mouse model to study the pathophysiology of sickle-cell disease-associated priapism. METHODS: Transgenic sickle-cell disease...

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PMID: 19523035
DOI: 10.1111/j.1743-6109.2009.01359.x

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