Article
Neurological effects of aromatase deficiency in the mouse.
The Journal of steroid biochemistry and molecular biology - 1 Sept 2003
Matsumoto Takahiro, Honda Shin-ichiro, Harada Nobuhiro
Abstract excerpt
In the brain, the conversion from androgen into estrogen is an important process for the differentiation of the brain function in male rodents. The aromatase is expressed in some nucleus of the brain. To assess the functional significance of the aromatase gene in development and activation of sex-specific behavior, we analyzed behavioral phenotypes of the aromatase knockout (ArKO) male mice. ArKO males obviously...
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