Article
Beta-globin gene cluster haplotypes and HbF levels are not the only modulators of sickle cell disease in Lebanon.
European journal of haematology - 1 Feb 2003
Inati A, Taher A, Bou Alawi W, Koussa S, Kaspar H, Shbaklo H, Zalloua P A
Abstract excerpt
Sickle cell disease (SCD) is an inherited autosomal recessive disorder of the beta-globin chain. Despite the fact that all subjects with SCD have the same single base pair mutation, the severity of the clinical and hematological manifestations is extremely variable. This study examined for the first time in Lebanon the correlation between the clinical manifestation of SCD and the beta-globin gene haplotypes. The...
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