Article
Pentanucleotide repeat polymorphism, lipoprotein(a) levels, and risk of ischemic heart disease.
The Journal of clinical endocrinology and metabolism - 1 Oct 2008
Kamstrup Pia R, Tybjaerg-Hansen Anne, Steffensen Rolf, Nordestgaard Børge G
Abstract excerpt
CONTEXT: Lipoprotein(a) is a cardiovascular risk factor. Levels of lipoprotein(a) are predominantly determined by apolipoprotein(a) gene variation, including a pentanucleotide repeat promoter polymorphism. OBJECTIVE: We tested the hypothesis that apolipoprotein(a) pentanucleotide repeat genotype predicts elevated lipoprotein(a) levels and risk of myocardial infarction (MI) and ischemic heart disease (IHD) in the...
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