Article
Genetic variations and humoral immune responses to myelin oligodendroglia glycoprotein in adult phenotypes of X-linked adrenoleukodystrophy.
Journal of neuroimmunology - 1 Feb 2003
Schmidt Stephan, Marrosu Giovanna Maria, Kölsch Heike, Haase Claus G, Ferenczik Stanislav, Sokolowski Piotr, Köhler Wolfgang, Schmidt Martina, Papassotiropoulos Andreas, Heun Reinhard, Grosse-Wilde Hans, Klockgether Thomas
Abstract excerpt
The lack of phenotype/genotype association in X-linked adrenoleukodystrophy (X-ALD) has prompted the search for disease modifying factors. We previously demonstrated increased serum antibody responses against myelin oligodendrocyte glycoprotein (MOG) in various clinical phenotypes of X-ALD allowing speculations that myelin specific humoral immune responses might be involved in phenotype generation of X-ALD. In...
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