Article
Th 1 cytokine production by peripheral blood mononuclear cells in X-linked adrenoleukodystrophy.
Journal of the neurological sciences - 1 Jan 2001
Di Biase A, Merendino N, Avellino C, Cappa M, Salvati S
Abstract excerpt
Cerebral adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN) are the two most frequent clinical phenotypes of the same genetic defect leading to the accumulation of very long chain fatty acids (VLCFA). Previous studies have suggested that inflammatory cytokines may play a role in the cerebral demyelination and in phenotype expression of the disease. We analyzed cytokine production by stimulated peripheral...
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