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Article

The myelin oligodendrocyte glycoprotein (MOG): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis.

Journal of neural transmission. Supplementum - 1 Jan 2000

Stefferl A, Brehm U, Linington C

Abstract excerpt

The myelin oligodendrocyte glycoprotein (MOG) is a major target for autoantibody mediated demyelination in experimental autoimmune encephalomyelitis (EAE). In the current review we discuss the epitope specificity of this antibody response, in particular evidence suggesting that pathogenic anti-MOG antibodies are preferentially directed against conformation-dependent epitopes present on the extracellular...

Topics

Animals
Antibody Formation
Autoantibodies
Demyelinating Diseases
Disease Models, Animal
Encephalomyelitis, Autoimmune, Experimental
Genetic Predisposition to Disease
Humans
Multiple Sclerosis
Myelin Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myelin-Associated Glycoprotein

Myelin-Oligodendrocyte Glycoprotein

Source

Identifiers

PMID: 11128602
DOI: 10.1007/978-3-7091-6284-2_10

Genes

MOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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The myelin oligodendrocyte glycoprotein (MOG): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis.PMID 11128602Read ↗

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Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): Insights into pathogenesis and biomarkers of prognosisSemantic proximity Read ↗

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