Serum autoantibody responses to myelin oligodendrocyte glycoprotein and myelin basic protein in X-linked adrenoleukodystrophy and multiple sclerosis.

doi:10.1016/s0165-5728(01)00345-9

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Article

Serum autoantibody responses to myelin oligodendrocyte glycoprotein and myelin basic protein in X-linked adrenoleukodystrophy and multiple sclerosis.

Journal of neuroimmunology - 3 Sept 2001

Schmidt S, Haase C G, Bezman L, Moser H, Schmidt M, Köhler W, Linington C, Klockgether T

Abstract excerpt

We analyzed the sera of 51 patients with various phenotypes of X-linked adrenoleukodystrophy (X-ALD), 20 patients with multiple sclerosis (MS) and 22 healthy volunteers for the presence of autoantibodies specific for the recombinant extracellular immunoglobulin-like domain of human myelin oligodendrocyte glycoprotein (rhMOG(Igd)) and myelin basic protein (MBP). Anti-rhMOG(Igd) autoantibodies were significantly...

Topics

Adolescent
Adrenoleukodystrophy
Adult
Autoantibodies
Female
Genetic Linkage
Humans
Male
Middle Aged
Multiple Sclerosis
Myelin Basic Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myelin Proteins

Myelin-Associated Glycoprotein

Myelin-Oligodendrocyte Glycoprotein

Phenotype

Recombinant Proteins

X Chromosome

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PMID: 11525804
DOI: 10.1016/s0165-5728(01)00345-9

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