Article
Isolation, characterization, and antifungal susceptibility of melanin-deficient mutants of Scedosporium prolificans.
Current microbiology - 1 Mar 2003
Ruiz-Díez Beatriz, Martínez-Suárez Joaquín V
Abstract excerpt
Scedosporium prolificans mutants lacking the ability to synthesize melanin were selected after ultraviolet light (UV) irradiation. UV exposure of S. prolificans conidia resulted in a high frequency of melanin-deficient (mel-) mutants. Stable and non-stable morphological variants were found in the population: reversion of the mutant phenotype was always to the wild-type phenotype. Based on their morphological...
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