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Article

Antioxidant function of fungal melanin.

Journal of bacteriology - 1 Nov 1993

Jacobson E S, Tinnell S B

Abstract excerpt

Polyphenols have been implicated in the virulence and oxidant resistance of Cryptococcus neoformans. Although monomeric polyphenols did not protect against the prooxidant, plumbagin, polymeric dopamine-melanin conferred resistance both to hypochlorite and to permanganate. The physiologic antioxidant capacity conferred by melanin was found to be 21.3 x 10(-15) mole-equivalents per cell, a value which approximates...

Topics

Antioxidants
Asparagine
Cryptococcus neoformans
Dopamine
Hypochlorous Acid
Kinetics
Melanins
Microbial Sensitivity Tests
Naphthoquinones
Oxidants
Phenotype
Potassium Permanganate

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Identifiers

PMID: 8226653
DOI: 10.1128/jb.175.21.7102-7104.1993
PMCID: PMC206840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8226653-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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