Article
Haplotype structure of TP53 locus in Indian population and possible association with head and neck cancer.
Annals of human genetics - 1 Jan 2003
Mitra S, Chatterjee S, Panda C K, Chaudhuri K, Ray K, Bhattacharyya N P, Sengupta A, Roychoudhury S
Abstract excerpt
It has been proposed that a constellation of three TP53 polymorphisms (intron 3 16 bp duplication, codon 72 BstUI, and intron 6 Nci I RFLP at nt 13494) constitute a haplotype predictive of increased cancer risk. We have estimated the allele frequency of these polymorphisms in three endogamous Indian ethnic populations from three different geographic locations (viz. Iyer from south India, Brahmin from central...
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