Article
The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia.
Diabetes care - 1 Feb 2003
Kubaszek Agata, Pihlajamäki Jussi, Karhapää Pauli, Vauhkonen Ilkka, Laakso Markku
Abstract excerpt
OBJECTIVE: To investigate the relationship of the K121Q polymorphism of the plasma cell glycoprotein 1 (PC-1) gene with insulin resistance, insulin secretion, and lipids and lipoproteins. RESEARCH DESIGN AND METHODS: Altogether, 110 normoglycemic subjects (group I) underwent a hyperinsulinemic-euglycemic clamp for evaluation of insulin sensitivity. The first-phase insulin secretion was determined by the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
