Article
The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.
Diabetes - 1 Sept 2000
Rasmussen S K, Urhammer S A, Pizzuti A, Echwald S M, Ekstrøm C T, Hansen L, Hansen T, Borch-Johnsen K, Frittitta L, Trischitta V, Pedersen O
Abstract excerpt
The human plasma-cell membrane differentiation antigen-1 (PC-1) has been shown to inhibit insulin receptor tyrosine kinase activity. Recently, a K121Q polymorphism in the human PC-1 gene was found in a Sicilian population and was shown to be strongly associated with insulin resistance. The object...
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