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Article

Atorvastatin dose-dependently decreases hepatic lipase activity in type 2 diabetes: effect of sex and the LIPC promoter variant.

Diabetes care - 1 Feb 2003

Berk-Planken Ingrid I L, Hoogerbrugge Nicoline, Stolk Ronald P, Bootsma Aart H, Jansen Hans

Abstract excerpt

OBJECTIVE: Hepatic lipase (HL) is involved in the metabolism of several lipoproteins and may contribute to the atherogenic lipid profile in type 2 diabetes. Little is known about the effect of cholesterol synthesis inhibitors on HL activity in relation to sex and the hepatic lipase gene, the LIPC promoter variant in type 2 diabetes. Therefore, we studied the effect of atorvastatin 10 mg (A10) and 80 mg (A80) on...

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Source

Identifiers

PMID: 12547874
DOI: 10.2337/diacare.26.2.427

Genes

LIPC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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