Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype.

Biochimica et biophysica acta - 1 Mar 2012

Brunzell John D, Zambon Alberto, Deeb Samir S

Abstract excerpt

Increased or decreased hepatic lipase (HL) activity has been associated with coronary artery disease (CAD). This is consistent with the findings that gene variants that influence HL activity were associated with increased CAD risk in some population studies but not in others. In this review, we will explain the conditions that influence the effects of HL on CAD. Increased HL is associated with smaller and denser...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Artery Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypercholesterolemia

Share to Hypertriglyceridemia

Share to Lipase

Share to Lipoproteins

Share to Obesity

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 21986251
DOI: 10.1016/j.bbalip.2011.09.008
PMCID: PMC3288605

Genes

CAD
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype.PMID 21986251Read ↗

Hepatic lipase, high density lipoproteins, and hypertriglyceridemia.Semantic proximity Read ↗

Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment.Semantic proximity Read ↗

Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet.Semantic proximity Read ↗

Low hepatic lipase activity is a novel risk factor for coronary artery disease.Semantic proximity Read ↗

Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol.Semantic proximity Read ↗

Hyperalphalipoproteinemia and Beyond: The Role of HDL in Cardiovascular DiseasesSemantic proximity Read ↗

Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis.Semantic proximity Read ↗

Hepatic lipase (LIPC) promoter polymorphism in men with coronary artery disease. Allele frequency and effects on hepatic lipase activity and plasma HDL-C concentrations.Semantic proximity Read ↗

Hepatic lipase: a marker for cardiovascular disease risk and response to therapy.Semantic proximity Read ↗

LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization studySemantic proximity Read ↗

Contribution of hepatic lipase, lipoprotein lipase, and cholesteryl ester transfer protein to LDL and HDL heterogeneity in healthy women.Semantic proximity Read ↗

Association between -514C-->T polymorphism of the hepatic lipase gene and coronary artery disease in a Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.