Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1999

Carr M C, Hokanson J E, Deeb S S, Purnell J Q, Mitchell E S, Brunzell J D

Abstract excerpt

High hepatic lipase (HL) activity is associated with an atherogenic lipoprotein profile of small, dense LDL particles and lower HDL(2)-C. Intra-abdominal fat (IAF) is positively associated with HL activity. A hepatic lipase gene (LIPC) promoter variant (G-->A(-250)) is associated with lower HL ac...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abdomen
Share to Adipose Tissue
Share to Cholesterol, HDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Lipase

Share to Multivariate Analysis

Share to Premenopause

Share to Triglycerides

Source

Identifiers

PMID: 10559014
DOI: 10.1161/01.atv.19.11.2701

Genes

LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10559014-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women.PMID 10559014Read ↗

The contribution of intraabdominal fat to gender differences in hepatic lipase activity and low/high density lipoprotein heterogeneity.Semantic proximity Read ↗

The G-250A polymorphism in the hepatic lipase gene promoter is associated with changes in hepatic lipase activity and LDL cholesterol: The KANWU Study.Semantic proximity Read ↗

Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet.Semantic proximity Read ↗

Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol.Semantic proximity Read ↗

Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. The LOCAT Study Invsestigators.Semantic proximity Read ↗

G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia.Semantic proximity Read ↗

The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis.Semantic proximity Read ↗

Promoter polymorphisms of hepatic lipase gene influence HDL(2) but not HDL(3) in African American men: CARDIA study.Semantic proximity Read ↗

Hepatic lipase, high density lipoproteins, and hypertriglyceridemia.Semantic proximity Read ↗

Hepatic lipase: a marker for cardiovascular disease risk and response to therapy.Semantic proximity Read ↗

Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment.Semantic proximity Read ↗

The -250G-->A polymorphism in the human hepatic lipase gene promoter affects blood lipids in Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.