Article
Common cholesteryl ester transfer protein gene polymorphisms and the effect of atorvastatin therapy in type 2 diabetes.
Diabetes care - 1 Apr 2003
van Venrooij Francine V, Stolk Ronald P, Banga Jan-Dirk, Sijmonsma Tjeerd P, van Tol Arie, Erkelens D Willem, Dallinga-Thie Geesje M
Abstract excerpt
OBJECTIVE: The cholesteryl ester transfer protein (CETP) plays a key role in the remodeling of triglyceride (TG)-rich and HDL particles. Sequence variations in the CETP gene may interfere with the effect of lipid-lowering treatment in type 2 diabetes. RESEARCH DESIGN AND METHODS: We performed a 30-week randomized double-blind placebo-controlled trial with atorvastatin 10 mg (A10) and 80 mg (A80) in 217 unrelated...
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