Article
Genetic analysis of hemostasis and thrombosis using vascular occlusion.
Blood cells, molecules & diseases - 1 Jan 2000
Gregory Michael, Hanumanthaiah Ravikumar, Jagadeeswaran Pudur
Abstract excerpt
The zebrafish is an excellent model for mammalian hemostasis and thrombosis since it possesses coagulation factors, thrombocyte receptors and responds to anti-coagulant and anti-platelet drugs commonly used in clinical treatment. In this study, exposure of larvae to FeCl(3) or laser irradiation produced a vessel injury that caused a visible vascular occlusion as a result of thrombus formation. Using the time to...
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