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Article

Axonal targeting of olfactory receptor neurons in Drosophila is controlled by Dscam.

Neuron - 23 Jan 2003

Hummel Thomas, Vasconcelos Maria Luisa, Clemens James C, Fishilevich Yelena, Vosshall Leslie B, Zipursky S Lawrence

Abstract excerpt

Different classes of olfactory receptor neurons (ORNs) in Drosophila innervate distinct targets, or glomeruli, in the antennal lobe of the brain. Here we demonstrate that specific ORN classes require the cell surface protein Dscam (Down Syndrome Cell Adhesion Molecule) to synapse in the correct glomeruli. Dscam mutant ORNs frequently terminated in ectopic sites both within and outside the antennal lobe. The...

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Identifiers

PMID: 12546818
DOI: 10.1016/s0896-6273(02)01183-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Axonal targeting of olfactory receptor neurons in Drosophila is controlled by Dscam.PMID 12546818Read ↗

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