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Article

The RAD30 cancer susceptibility gene.

Biochemical Society transactions - 1 Feb 2003

Carty M P, Glynn M, Maher M, Smith T, Yao J, Dixon K, McCann J, Rynn L, Flanagan A

Abstract excerpt

The human skin cancer-prone disease xeroderma pigmentosum variant (XPV) results from a mutation in RAD30, which encodes the novel lesion bypass DNA polymerase eta. XPV cells are characterized by delayed completion of DNA replication and increased mutagenesis following UV irradiation. In cell-free extracts of XPV lymphoblasts, functional DNA polymerase eta is required for the complete replication of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12546696
DOI: 10.1042/bst0310252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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