Article

POLQ variants with aberrant DNA polymerase activity protect against UV-induced cell death

2025-11-28

Abstract excerpt

<h4>ABSTRACT</h4> DNA polymerases are important for maintaining genomic stability by protecting against mutagenic lesions caused by external and internal factors. If left unrepaired, DNA damage can lead to replication errors resulting in changes in DNA sequences that could impact peptide sequences and gene expression, as well as lead to chromosomal breaks. Highlighting the importance of DNA polymerase repair func...

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Literature Corpus work: 0fe86235-f112-5097-aa09-11c72cb00c4b
DOI: 10.1101/2025.11.26.690880

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