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Article

Age-related changes in expression of transforming growth factor-β and receptors in cells of intervertebral discs

1 Jan 2003

Abstract excerpt

OBJECT: The authors conducted a study to determine age-related changes in expression of transforming growth factor (TGF)-beta1, -beta2, -beta3, and Type I and Type II receptors in various cells in the nucleus pulposus and anulus fibrosus. Immunolocalization of TGFbetas and Type I and II receptors was examined during the aging process of cervical intervertebral discs in senescence-accelerated mice (SAM). The...

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Share to Cervical and Thoracic Myelopathy
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Identifiers

PMID: 12546390
DOI: 10.3171/spi.2003.98.1.0063

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