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Article

E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation.

American journal of physiology. Heart and circulatory physiology - 1 May 2003

Chu Xin, Chen Ju, Reedy Mary C, Vera Carlos, Sung K-L Paul, Sung Lanping Amy

Abstract excerpt

Tropomodulins are a family of proteins that cap the slow-growing end of actin filaments. Erythrocyte tropomodulin (E-Tmod) stabilizes short actin protofilaments in erythrocytes and caps longer sarcomeric actin filaments in striated muscles. We report the knockin of the beta-galactosidase gene (LacZ) under the control of the endogenous E-Tmod promoter and the knockout of E-Tmod in mouse embryonic stem cells....

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Identifiers

PMID: 12543641
DOI: 10.1152/ajpheart.00947.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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