Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease.

Hepatology (Baltimore, Md.) - 1 Feb 2003

Vidali Matteo, Stewart Stephen F, Rolla Roberta, Daly Ann K, Chen Yuanneng, Mottaran Elisa, Jones David E J, Leathart Julian B, Day Christopher P, Albano Emanuele

Abstract excerpt

Autoimmune reactions are often associated with alcoholic liver disease; however, the mechanisms responsible are largely unknown. This study investigates the potential role of the immune response against hydroxyethyl free radical (HER)-derived antigens and of polymorphisms in immunoregulatory genes in the development of anti-cytochrome P4502E1 (CYP2E1) autoantibodies in alcohol abusers. Immunoglobulin G (IgG)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abatacept
Share to Antibody Formation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Differentiation

Share to Cytochrome P-450 CYP2E1

Share to Fatty Liver

Share to Immune System

Share to Immunoconjugates

Share to Liver Cirrhosis, Alcoholic

Source

Identifiers

PMID: 12540792
DOI: 10.1053/jhep.2003.50049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease.PMID 12540792Read ↗

Alcohol and Cancer: Mechanisms and Therapies.Semantic proximity Read ↗

Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms and susceptibility to type 1 autoimmune hepatitis.Semantic proximity Read ↗

Genetic variants of TNFα, IL10, IL1β, CTLA4 and TGFβ1 modulate the indices of alcohol-induced liver injury in East Indian population.Semantic proximity Read ↗

Genetic polymorphism of cytochrome P4502E1 and risk of alcoholic liver disease in Caucasians.Semantic proximity Read ↗

[Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis].Semantic proximity Read ↗

Genetic polymorphisms of aldehyde dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the liver due to its polymorphism.Semantic proximity Read ↗

Oxidative stress-related enzyme polymorphisms associated with the immunological biomarkers levels in heavy drinkers in Taiwan.Semantic proximity Read ↗

Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease.Semantic proximity Read ↗

Association of a restriction fragment length polymorphism in the alcohol dehydrogenase 2 gene with Japanese alcoholic liver cirrhosis.Semantic proximity Read ↗

Who gets alcoholic liver disease: nature or nurture?Semantic proximity Read ↗

Genetic polymorphisms influencing xenobiotic metabolism and transport in patients with primary biliary cirrhosis.Semantic proximity Read ↗

HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.