Article
Simulating haplotype blocks in the human genome.
Bioinformatics (Oxford, England) - 22 Jan 2003
Posada David, Wiuf Carsten
Abstract excerpt
SUMMARY: A bioinformatic tool was written to simulate haplotypes and SNPs under a modified coalescent with recombination. The most important feature of this program is that it allows for the specification of non-homogeneous recombination rates, which results in the formation of the so-called 'haplotype blocks' of the human genome. The program also implements different mutation models and flexible demographic...
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