CYP2D6 genotype determination in the Danish population.

doi:10.1007/BF02570501

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Article

CYP2D6 genotype determination in the Danish population.

European journal of clinical pharmacology - 1 Jan 1994

Brøsen K, Nielsen P N, Brusgaard K, Gram L F, Skjødt K

Abstract excerpt

CYP2D6 genotyping was carried out by XbaI restriction fragment length polymorphism analysis and polymerase chain reaction in 168 healthy Danish volunteers, 77 extensive metabolizers (EM) and 91 poor metabolizers (PM) of sparteine. All EM were genotyped correctly as heterozygous or homozygous for...

Topics

Adolescent
Adult
Alleles
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Debrisoquin
Deoxyribonucleases, Type II Site-Specific
Female
Genetics, Population
Genotype
Homozygote
Humans
Male
Middle Aged
Mixed Function Oxygenases
Mutation
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 7867674
DOI: 10.1007/BF02570501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7867674-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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