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Article

An insertion/deletion polymorphism in the alpha2B-adrenergic receptor gene is a novel genetic risk factor for acute coronary events.

Journal of the American College of Cardiology - 1 May 2001

Snapir A, Heinonen P, Tuomainen T P, Alhopuro P, Karvonen M K, Lakka T A, Nyyssönen K, Salonen R, Kauhanen J, Valkonen V P, Pesonen U, Koulu M, Scheinin M, Salonen J T

Abstract excerpt

OBJECTIVES: Our aim was to study whether an insertion/deletion (I/D) polymorphism in the alpha2B-adrenoceptor gene is associated with the risk for cardiovascular diseases. BACKGROUND: alpha2-adrenoceptors mediate contraction of vascular smooth muscle and induce coronary vasoconstriction in humans...

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Blood Pressure
Coronary Disease
Finland
Genetic Carrier Screening
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Population Surveillance

Proportional Hazards Models

Receptors, Adrenergic, alpha-2

Source

Identifiers

PMID: 11345359
DOI: 10.1016/s0735-1097(01)01201-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11345359-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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