Article
Identification of genes that function in the biogenesis and localization of small nucleolar RNAs in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jun 2008
Qiu Hui, Eifert Julia, Wacheul Ludivine, Thiry Marc, Berger Adam C, Jakovljevic Jelena, Woolford John L, Corbett Anita H, Lafontaine Denis L J, Terns Rebecca M, Terns Michael P
Abstract excerpt
Small nucleolar RNAs (snoRNAs) orchestrate the modification and cleavage of pre-rRNA and are essential for ribosome biogenesis. Recent data suggest that after nucleoplasmic synthesis, snoRNAs transiently localize to the Cajal body (in plant and animal cells) or the homologous nucleolar body (in budding yeast) for maturation and assembly into snoRNPs prior to accumulation in their primary functional site, the...
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