Article
The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits.
The EMBO journal - 1 Jul 1994
Sun C, Woolford J L
Abstract excerpt
The Saccharomyces cerevisiae NOP4 gene was isolated by screening a lambda gt11 yeast genomic DNA library with a monoclonal antibody against a yeast nucleolar protein. NOP4 encodes a 78 kDa protein that contains two prototypical RNA recognition motifs (RRMs) flanking an imperfect RRM lacking chara...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genes, Lethal
- Molecular Sequence Data
- Nuclear Proteins
- RNA Precursors
- RNA Processing, Post-Transcriptional
- RNA, Fungal
- RNA, Ribosomal
- Recombinant Fusion Proteins
- Restriction Mapping
- Ribonucleoproteins, Small Nucleolar
- Ribosomes