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Article

Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis

1 Dec 2002

Abstract excerpt

Skeletogenesis occurs through either intramembranous or endochondral ossification. In addition, some parts of the skeletal components maintain their cartilaginous characteristics throughout life without mineralization. Runx2 is known to be a pivotal transcription factor for all skeletogenic processes. In this study, we examined the expression patterns of two major isoforms of Runx2 in early skeletogenesis. During...

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PMID: 12526084
DOI: 10.1038/emm.2002.60

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