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Article

Host genetic influences on HIV-1 pathogenesis.

Current opinion in immunology - 1 Aug 1999

Michael N L

Abstract excerpt

Cellular entry of HIV-1 is mediated by interaction with CD4 and chemokine receptors that serve as entry coreceptors. The immune response against HIV-1 is regulated by genes of the HLA locus. Genetic polymorphisms in these genes have recently been associated with effects on HIV-1 pathogenesis. The history and implications of these discoveries are described in this review.

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Share to Acquired Immunodeficiency Syndrome
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptors, CCR5

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Source

Identifiers

PMID: 10448150
DOI: 10.1016/S0952-7915(99)80078-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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