GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

Molecular medicine (Cambridge, Mass.) - 1 Nov 2002

Annerén Cecilia, Welsh Michael

Abstract excerpt

BACKGROUND: Insulin receptor substrate proteins (IRS) mediate various effects of insulin, including regulation of glucose homeostasis, cell growth and survival. To understand the underlying mechanisms explaining the effects of the Src-related tyrosine kinase GTK on beta-cell proliferation and survival, insulin-signalling pathways involving IRS-1 and IRS-2 were studied in islet cells and RINm5F cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insulin-Like Growth Factor I
Share to Insulin Receptor Substrate Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Islets of Langerhans

Share to Mice, Inbred CBA

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to Mitogen-Activated Protein Kinases

Share to Proto-Oncogene Proteins c-akt

Source

Open in PubMed Open full text

Identifiers

PMID: 12520087
PMCID: PMC2039956

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.