Article
Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese.
The Journal of clinical endocrinology and metabolism - 1 Jan 2003
Horikawa Yukio, Oda Naohisa, Yu Li, Imamura Shigeo, Fujiwara Kentaro, Makino Masaki, Seino Yutaka, Itoh Mitsuyasu, Takeda Jun
Abstract excerpt
The 112/121 haplotype combination defined by the UCSNP-43, -19, and -63 alleles in the calpain-10 gene is associated with type 2 diabetes in Mexican Americans. To determine whether this genetic variation constitutes risk of type 2 diabetes in Japanese, we investigated its frequency in 177 patients with type 2 diabetes and 172 controls. Though this variation occurs in Japanese more frequently than in Mexican...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
