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Article

Human immunodeficiency virus type 1 subtype C exhibits higher transactivation activity of Tat than subtypes B and E.

Microbiology and immunology - 1 Jan 2002

Kurosu Takeshi, Mukai Tetsu, Komoto Satoshi, Ibrahim Madiha S, Li Yong-Gang, Kobayashi Takeshi, Tsuji Shoutaro, Ikuta Kazuyoshi

Abstract excerpt

Although human immunodeficiency virus type 1 (HIV-1) subtypes C and E are expanding faster and seem to be of greater global significance than HIV-1 subtype B, there is only little information about Tat activity of such non-B subtypes. Here, we showed evidence that subtype C Tat exhibits higher transcriptional activity from the HIV-1 long-terminal repeat (LTR) in a human T-cell line, compared with subtypes B and...

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Share to CD4-Positive T-Lymphocytes
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Products, tat

Share to HIV Long Terminal Repeat

Share to Mutagenesis, Site-Directed

Share to tat Gene Products, Human Immunodeficiency Virus

Share to Transcriptional Activation

Source

Identifiers

PMID: 12516777
DOI: 10.1111/j.1348-0421.2002.tb02766.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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