Article
HIV Tat protein: Is Tat-C much trickier than Tat-B?
Journal of medical virology - 1 Aug 2015
Johri Manish Kumar, Sharma Nikhil, Singh Sunit K
Abstract excerpt
Out of various subtypes of human immunodeficiency virus type 1 (HIV-1), subtype B and C cause most of the infections worldwide. Clade specific differences have been reported in differences in clinical picture of HIV pathogenesis. Transcription of the HIV-1 genome is regulated by the interaction of HIV Tat protein to the trans-activation response (TAR) element. The differential binding of clade B and C Tat...
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