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Article

HIV-1C and HIV-1B Tat protein polymorphism in Southern Brazil.

Journal of neurovirology - 1 Feb 2021

de Almeida Sérgio Monteiro, Rotta Indianara, Vidal Luine Rosele Renaud, Dos Santos Jucelia Stadinicki, Nath Avindra, Johnson Kory, Letendre Scott, Ellis Ronald J

Abstract excerpt

The transactivator of transcription (Tat) is a key HIV regulatory protein. We aimed to identify the frequency of key polymorphisms in HIV-1C compared with HIV-1B Tat protein, chiefly in the cysteine-, arginine-, and glutamine-rich domains and identify novel point mutations in HIV-1B and C sequences from Southern Brazil. This study was the first to investigate the genetic diversity and point mutations within HIV-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to tat Gene Products, Human Immunodeficiency Virus

Source

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Identifiers

PMID: 33462791
DOI: 10.1007/s13365-020-00935-z
PMCID: PMC8510567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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