Article
Vitamin A (retinoids) regulation of mouse melanoma growth and differentiation.
The Journal of nutrition - 1 Jan 2003
Niles Richard M
Abstract excerpt
The incidence of melanoma is rapidly increasing in the U.S. population. At the present, there is no effective chemotherapy against invasive melanoma. At our laboratory, we have been studying retinoic acid (RA)-induced growth arrest and differentiation in the B16 murine melanoma cell model. Several immediate-early gene targets of RA were identified by gene arrays. In one of these genes, T-box binding protein-2...
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