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Article

Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 2003

Prevot Vincent, Rio Carlos, Cho Gyeong J, Lomniczi Alejandro, Heger Sabine, Neville Craig M, Rosenthal Nadia A, Ojeda Sergio R, Corfas Gabriel

Abstract excerpt

The initiation of mammalian puberty requires the activation of hypothalamic neurons secreting the neuropeptide luteinizing hormone-releasing hormone (LHRH). It is thought that this activation is caused by changes in trans-synaptic input to LHRH neurons. More recently, it has been postulated that the pubertal increase in LHRH secretion in female animals also requires neuron-glia signaling mediated by growth...

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Source

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Identifiers

PMID: 12514220
PMCID: PMC6742140

Genes

EGF
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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