Article

Establishment of a novel fetal ovine heart cell line by spontaneous cell fusion

2022-07-16

Abstract excerpt

We established a unique immortal cell line designated, FOH-SA, by serial passage of fetal ovine heart cells. In a novel phenomenon in cell biology, we demonstrated that the immortalization of the line supervened as a result of spontaneous cellular and nuclear fusion of two morphologically distinct cardiocytes in passage 29. Fused cells gave progeny cells which grew into multicellular filaments. Trypsinization of t...

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Literature Corpus work: c6a375c2-2b80-59de-a526-ce564243835b
DOI: 10.1101/2022.07.14.500071

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