Article
A prospective study characterizing full-length hepatitis B virus genomes during acute exacerbation.
Gastroenterology - 1 Jan 2003
Liu Chun-Jen, Chen Pei-Jer, Lai Ming-Yang, Kao Jia-Horng, Chang Ching-Fung, Wu Hui-Lin, Shau Wen-Yi, Chen Ding-Shinn
Abstract excerpt
BACKGROUND & AIMS: Hepatitis B virus (HBV) evolves rapidly in patients with chronic hepatitis B, and HBV variation may trigger acute exacerbation. To study this relationship, we investigated full-length viral sequences before, during, and after exacerbation. METHODS: We prospectively studied 14 patients with exacerbation of hepatitis B, either spontaneously (n = 4) or after receiving various medical interventions...
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