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Article

Chronic Hepatitis B with Spontaneous Severe Acute Exacerbation.

International journal of molecular sciences - 26 Nov 2015

Tsai Wei-Lun, Sun Wei-Chi, Cheng Jin-Shiung

Abstract excerpt

Chronic hepatitis B virus (HBV) infection is a major global health problem with an estimated 400 million HBV carriers worldwide. In the natural history of chronic hepatitis B (CHB), spontaneous acute exacerbation (AE) is not uncommon, with a cumulative incidence of 10%-30% every year. While exacerbations can be mild, some patients may develop hepatic decompensation and even die. The underlying pathogenesis is...

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Identifiers

PMID: 26703566
DOI: 10.3390/ijms161226087
PMCID: PMC4691034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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