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Article

High replicative full-length lamivudine-resistant hepatitis B virus isolated during acute exacerbations.

Journal of medical virology - 1 Oct 2005

Zhang Ji-Ming, Yao Xin, Wang Yong-Xiang, Liu Fang, Ma Zhang-Mei, Weng Xing-Hua, Wen Yu-Mei

Abstract excerpt

During chronic HBV infections, exacerbations of disease usually occur without clearly understood mechanisms. In this study, full-length HBV genomes were analyzed from four chronic hepatitis B patients who developed resistance to lamivudine [-2'-deoxy-3'-thiacytidine, LMV] accompanied by acute exacerbation of disease. Paired full-length HBV isolates were cloned from the sera of patients prior to LMV treatment and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16121368
DOI: 10.1002/jmv.20453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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