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Article

Association of the TNF +489 polymorphism with susceptibility and radiographic damage in rheumatoid arthritis.

Genes and immunity - 1 Nov 1999

van Krugten M V, Huizinga T W, Kaijzel E L, Zanelli E, Drossaers-Bakker K W, van de Linde P, Hazes J M, Zwinderman A H, Breedveld F C, Verweij C L

Abstract excerpt

Multiple genetic factors contribute to susceptibility to rheumatoid arthritis (RA). The extent of variability in disease presentation in RA may be related to genetic heterogeneity. In this study we investigated the association of the TNF gene polymorphism at position +489 with susceptibility to and severity of RA. Analysis of the frequency of the +489 A and G alleles in a group of 293 consecutive RA patients and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11196668
DOI: 10.1038/sj.gene.6363632

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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