Article
Haplotype sharing analysis with SNPs in candidate genes: the Genetic Analysis Workshop 12 example.
Genetic epidemiology - 1 Jan 2003
Fischer Christine, Beckmann Lars, Majoram Paul, te Meerman Gerard, Chang-Claude Jenny
Abstract excerpt
Haplotype sharing analysis was used to investigate the association of affection status with single nucleotide polymorphism (SNP) haplotypes within candidate gene 1 in one sample each from the isolated and the general population of Genetic Analysis Workshop (GAW) 12 simulated data. Gene 1 has direct influence on affection and harbors more than 70 SNPs. Haplotype sharing analysis depends heavily on previous...
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