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Article

Haplotype sharing analysis in affected individuals from nuclear families with at least one affected offspring.

Genetic epidemiology - 1 Jan 1997

Van der Meulen M A, te Meerman G J

Abstract excerpt

In diseases with a complex mode of inheritance, families with multiple affected individuals are difficult to ascertain. The haplotype sharing statistic (HSS) uses (hidden) co-ancestry between affected individuals from a founder population. These affected individuals will likely not only share the same mutation(s), but also the surrounding haplotype. We show that this method gives a low false positive rate, but...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9433600
DOI: 10.1002/(SICI)1098-2272(1997)14:6<915::AID-GEPI59>3.0.CO;2-P

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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