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Article

In Vivo Determination of Muscarinic Acetylcholine Receptor Availability in Schizophrenia

27 Dec 2002

Abstract excerpt

OBJECTIVE: Postmortem studies have implicated the central muscarinic acetylcholine system in schizophrenia. However, central muscarinic receptor availability has not previously been studied in vivo. Using [I-123]iodoquinuclidinyl benzilate ([(123)I]IQNB) single photon emission computed tomography (SPECT), the authors sought to compare the muscarinic receptor availability in vivo in unmedicated patients with...

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PMID: 12505810
DOI: 10.1176/appi.ajp.160.1.118

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